2C-B (4-bromo-2,5-dimethoxyphenethylamine) is a synthetic psychoactive substance of the phenethylamine family. It's known for its hallucinogenic properties similar to LSD, but with a shorter duration of action.

Detoxification from 2C-B is primarily focused on managing psychological symptoms, as it is primarily a psychedelic with fewer physical withdrawal symptoms. Treatment may involve a safe, supportive environment, monitoring for any severe psychological reactions, and possibly using medications to treat anxiety or psychotic symptoms if they arise.

Use of 2C-B is associated with an increased risk of psychotic disorders, anxiety, and depression, especially in those with a predisposition to these conditions.

2C-B is sometimes used in combination with other hallucinogens like LSD or MDMA, though this increases the risks of unpredictable psychological effects.